Fig. 9
From: Attenuated Ca2+ release in a mouse model of limb girdle muscular dystrophy 2A
Ca2+ release domains in WT and C3KO fibers. a Tridimensional representation of Ca2+ release elicited by action potentials in a WT fiber. Confocal recordings were performed in positions separated by 200 nm along a ~6-μm stretch aligned parallel to the fiber long axis. b Intensity contour map representation of the data in (a). c, d The corresponding representations of confocal data recorded from a C3KO fiber. The same pseudocolor codification was used for all data. The arrows in (a) and (c) indicate the positions of M lines. The red and green lines in (b) and (d) indicate the positions of M and Z lines, respectively. The sarcomere length was 2.1 μm for both WT and C3KO fibers