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Table 1 CLAMS analysis of 10-week-old TSCmKO and RAmKO mice

From: Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

 

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TSCmKO

P

Ctrl

RAmKO

P

Drink (ml/g/day)

0.31 ± 0.04

0.34 ± 0.06

NS

0.28 ± 0.04

0.30 ± 0.10

NS

Feed (g/g/day)

0.58 ± 0.17

0.58 ± 0.05

NS

0.42 ± 0.06

0.60 ± 0.14

*

CO2 (l/g/day)

0.37 ± 0.02

0.36 ± 0.03

NS

0.34 ± 0.04

0.41 ± 0.03

*

O2 (l/g/day)

0.39 ± 0.02

0.38 ± 0.02

NS

0.37 ± 0.05

0.44 ± 0.04

*

RER

0.94 ± 0.01

0.93 ± 0.03

NS

0.90 ± 0.01

0.91 ± 0.01

NS

Heat (kcal/h/g)

0.020 ± 0.00

0.019 ± 0.00

NS

0.026 ± 0.00

0.032 ± 0.00

*

X-amb (counts/h)

1078.9 ± 230.2

938.66 ± 314.8

NS

935.3 ± 357.3

938.7 ± 314.8

NS

Y-amb (counts/h)

187.9 ± 45.8

186.1 ± 51.6

NS

169.50 ± 93.17

140.19 ± 61.47

NS

  1. Student’s t test. Values represent mean ± SEM over a period of 3 days. Data presented are of male mice. X-amb and Y-amb refer to ambulatory movement measured by laser counts in X and Y coordinates
  2. NS not significant
  3. *p < 0.05 (n = 6)