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Fig. 12 | Skeletal Muscle

Fig. 12

From: The SH3 and cysteine-rich domain 3 (Stac3) gene is important to growth, fiber composition, and calcium release from the sarcoplasmic reticulum in postnatal skeletal muscle

Fig. 12

Electrostimulation- and caffeine-induced increases in intracellular calcium in FDB myofibers from tamoxifen-injected Stac3 fl/fl and Stac3 fl/fl Tg Cre mice at 8 weeks of age. The FDB myofibers from mice 4 weeks after tamoxifen injection were loaded with the fluorescent calcium indicator Fura-4F. Fluorescence emission was recorded by a microscope. a Representative raw Fura-4F traces. b Quantification of frequent electrostimulation-induced increases in intracellular calcium concentration. Asterisks indicate P < 0.05, Stac3 fl/fl Tg Cre versus Stac3 fl/fl at the same frequency (n = 37, 18 fibers for Stac3 fl/fl Tg Cre and Stac3 fl/fl, respectively). c Quantification of caffeine-induced percentage changes in intracellular calcium concentration. Asterisk indicates P < 0.05, Stac3 fl/fl Tg Cre versus Stac3 fl/fl

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Skeletal Muscle

ISSN: 2044-5040

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