Fig. 8From: Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosisEC coupling is impaired in MLC/SOD1G93A FDB fibers. Representative Ca2+ transients elicited by 25 ms depolarizations from −80 to −60, −40, −20, 0, and 20 mV in fibers obtained from a wild-type FVB/NJ mouse (a) and a MLC/SOD1G93A mouse (b). ΔF/F-V relationships are shown in (c)Back to article page