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Fig. 1 | Skeletal Muscle

Fig. 1

From: Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

Fig. 1

Susceptibility to contraction-induced muscle injury, i.e., force drop following lengthening contractions in TA muscle from mdx mice and neuromuscular transmission. a Example of force traces during lengthening contractions in mdx mice. The 10th contraction was isometric. b Force drop following lengthening and isometric contractions in mdx and C57 mice. c Force drop following nine lengthening contractions in mdx mice, recovery, and direct muscle stimulation with high voltage. Mdx LC lengthening contractions in mdx mice, Mdx IC isometric contractions in mdx mice, C57 LC lengthening contractions in C57 mice, 0LC before lengthening contractions, 9LC after nine lengthening contractions, 9LC + muscle stimul stimulating electrodes were located on the muscle after the ninth contractions, 9LC + recovery 30 min force was measured 30 min after the ninth lengthening contractions, a significantly different from before lengthening contractions (p < 0.05), b significant difference between strains (p < 0.05), c significant difference from 9LC (p < 0.05). n = 8–21 per group

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Skeletal Muscle

ISSN: 2044-5040

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