Aims and scope

Aims and scope

Skeletal Muscle is a peer-reviewed, open access, online journal that publishes articles investigating molecular mechanisms underlying the biology of skeletal muscle. A wide range of skeletal muscle biology is included: development, metabolism, the regulation of mass and function, aging, degeneration, dystrophy and regeneration. The emphasis is on understanding adult skeletal muscle, its maintenance, and its interactions with non-muscle cell types and regulatory modulators.

Skeletal Muscle aims to provide a venue for the publication of novel, cutting-edge research and technological developments involving the application of molecular biology, cellular biology, and biochemistry-based approaches, and to answer questions relevant to the understanding of skeletal muscle.

Main areas of interest include:

  • differentiation of skeletal muscle
  • atrophy and hypertrophy of skeletal muscle
  • aging of skeletal muscle
  • regeneration and degeneration of skeletal muscle
  • biology of satellite and satellite-like cells
  • dystrophic degeneration of skeletal muscle
  • energy and glucose homeostasis in skeletal muscle
  • non-dystrophic genetic diseases of skeletal muscle, such as Spinal Muscular Atrophy and myopathies
  • maintenance of neuromuscular junctions
  • roles of ryanodine receptors and calcium signaling in skeletal muscle
  • roles of nuclear receptors in skeletal muscle
  • roles of GPCRs and GPCR signaling in skeletal muscle
  • other relevant aspects of skeletal muscle biology

In addition, articles on translational clinical studies that address molecular and cellular mechanisms of skeletal muscle will be published. Case reports are also encouraged for submission.

Skeletal Muscle reflects the breadth of research on skeletal muscle and bridges gaps between diverse areas of science for example cardiac cell biology and neurobiology, which share common features with respect to cell differentiation, excitatory membranes, cell-cell communication, and maintenance. Suitable articles are model and mechanism-driven, and apply statistical principles where appropriate; purely descriptive studies are of lesser interest.

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