Figure 6From: Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesisRelationship between muscle protein fractional synthetic rate (FRS) and extent of phosphorylation of S6 kinase (S6K)1 and mammalian target of rapamycin (mTOR), at 24 hours after exercise. There was a significant relationship (P = 0.01) between the degree of phosphorylation of mTOR (Ser2448) (AU) and mixed muscle protein fractional synthetic rate (%/hour) at 24 hours after exercise in (A) the young group only, with (B) no significant relationship seen in the older group (P = 0.71). There was a significant relationship (P = 0.04) between the degree of phosphorylation of S6K1 (Thr389) (AU) and mixed muscle protein fractional synthetic rate (%/hour) at 24 hours after exercise in (C) young group only, with (D) no significant relationship seen in the older group (P = 0.69). Note: some points overlaid.Back to article page