Skip to main content
Figure 6 | Skeletal Muscle

Figure 6

From: Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

Figure 6

Relationship between muscle protein fractional synthetic rate (FRS) and extent of phosphorylation of S6 kinase (S6K)1 and mammalian target of rapamycin (mTOR), at 24 hours after exercise. There was a significant relationship (P = 0.01) between the degree of phosphorylation of mTOR (Ser2448) (AU) and mixed muscle protein fractional synthetic rate (%/hour) at 24 hours after exercise in (A) the young group only, with (B) no significant relationship seen in the older group (P = 0.71). There was a significant relationship (P = 0.04) between the degree of phosphorylation of S6K1 (Thr389) (AU) and mixed muscle protein fractional synthetic rate (%/hour) at 24 hours after exercise in (C) young group only, with (D) no significant relationship seen in the older group (P = 0.69). Note: some points overlaid.

Back to article page