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Figure 2 | Skeletal Muscle

Figure 2

From: δ-Sarcoglycan-deficient muscular dystrophy: from discovery to therapeutic approaches

Figure 2

Putative pathomechanisms involved in δ-sarcoglycanopathy revealed by studies of the animal models of the disease. Disease mechanisms suggested by animal studies, and their possible relationships to each other, are presented schematically. Pivotal events in the development of pathology are highlighted in red, and potential therapies are shown in blue. Faded boxes represent therapies that have had some success in animal models of other muscular dystrophies or are currently used in Duchenne muscular dystrophy and as such may be potentially useful in the treatment of δ-sarcoglycanopathy.

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