Figure 5
Removal of extracellular calcium or addition of streptomycin does not affect immediate force loss during eccentric muscle contractions in mdx mice. (A) Eccentric contractions performed in calcium-free buffer (CaCl2 replaced with MgCl2). (B) Eccentric contractions performed in calcium-free buffer with the addition of 1 mM ethylene glycol tetraacetic acid (EGTA). (C) Eccentric contractions performed in normal buffer with the addition of 2 mM streptomycin. Data are means ± SEM. *Statistically significant difference from Krebs-Ringer bicarbonate buffer.