Skip to main content
Figure 4 | Skeletal Muscle

Figure 4

From: IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse

Figure 4

IL-6 inhibition restores mitochondrial dynamics and reduces apoptosis in the ApcMin/+mouse. A) Representative Western blot of Mfn2 and FIS1 protein expression in wild-type and ApcMin/+ mice treated with an IL-6 receptor antibody or PBS control. B) Mfn2 and C) FIS1 protein expression normalized to PBS treated wild-type mice. D) Bax mRNA expression normalized to PBS treated wild-type mice. Values are means ± SE. Significance was set at P <0.05. * Signifies the difference within treatment. † Signifies the difference within genotype.

Back to article page