Figure 2
From: The superhealing MRL background improves muscular dystrophy
The MRL genome quantitatively reduces fibrosis in Sgcg mice. Hydroxyproline (HOP) is a measure of fibrosis and is represented on the y axis (mM/mg). In the heart, diaphragm and quadriceps muscles, fibrosis is significantly (p < 0.001) reduced in intercrossed SgcgMRL/D2 (D2/MRL) animals compared to Sgcg in the D2 (D2) background at 8 weeks. Fibrosis remains significantly (***p < 0.001) reduced in SgcgMRL/D2 animals at the 32-week time point.