Figure 1
From: Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma
Addition of Rb1 inactivation to Pax3:Foxo1a activation and p53 deletion changes gene expression features for tumors in the Myf6cre lineage. (A) qRT-PCR of Pax3:Foxo1a shows similar expression level in strains with Pax3:Foxo1a,p53 versus Pax3:Foxo1a,p53,Rb1 mice. (B) Expression of tumor subtype-specific markers in Pax3:Foxo1a,p53 versus Pax3:Foxo1a,p53,Rb1 versus p53 mice.