Figure 7
From: Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma
pRb expression in human RMS. (A) Western blotting of human aRMS (Rh30,Rh41) and eRMS (Rh18, RD) cell lines. (B) Clinical RMS samples. alv, aRMS; emb, eRMS; ana, with anaplasia; pleo, pleomorphic RMS. (C) to (H) Immunohistochemistry of a human rhabdomyosarcoma tissue microarray using an anti-phospho pRb antibody that detects phosphorylation at Ser807/811. Staining was nuclear, cytoplasmic or both in any given cell, but the percentage of cells stained variably between 0 and 80%.