Skip to main content

Table 1 Principal component analysis from different 4 studies

From: Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma

Dataset Number of signature genes Number of genes mapped to microarray Reference
Differentially expressed genes in fusion-positive aRMS vs. fusion-negative eRMS 121 83 Laé and colleagues [19]
Genes differentially expressed between PAX-FOXO1A and fusion-negative RMS cell lines 79 55 Davicioni and colleagues [14]
Williamson F1/F2 metagenes 45 32 Williamson and colleagues [20]
Genes conserved in mouse and human Pax3:Foxo1a-positive aRMS 58 47 Nishijo and colleagues [11]
  1. All human gene symbols were translated to their homologues in mouse using MammalHom (http://depts.washington.edu/l2l/mammalhom.html) and then mapped to the microarray annotation. aRMS, alveolar rhabdomyosarcoma; eRMS, embryonal rhabdomyosarcoma; RMS, rhabdomyosarcoma.