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Table 1 Principal component analysis from different 4 studies

From: Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma

Dataset

Number of signature genes

Number of genes mapped to microarray

Reference

Differentially expressed genes in fusion-positive aRMS vs. fusion-negative eRMS

121

83

Laé and colleagues [19]

Genes differentially expressed between PAX-FOXO1A and fusion-negative RMS cell lines

79

55

Davicioni and colleagues [14]

Williamson F1/F2 metagenes

45

32

Williamson and colleagues [20]

Genes conserved in mouse and human Pax3:Foxo1a-positive aRMS

58

47

Nishijo and colleagues [11]

  1. All human gene symbols were translated to their homologues in mouse using MammalHom (http://depts.washington.edu/l2l/mammalhom.html) and then mapped to the microarray annotation. aRMS, alveolar rhabdomyosarcoma; eRMS, embryonal rhabdomyosarcoma; RMS, rhabdomyosarcoma.