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Table 3 Most frequent domains in the LGMD-centered dataset and representativeness in the human proteome

From: A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

Domains

% in the total of SID

% in the human proteome (according to Müller et al., Genome Res 2002)

Immunoglobulin (IPR003599; IPR003598; IPR007110)

22.5% (n=141)

4.2% (n=1214; r=2)

Zinc finger, C2H2-type (IPR007087)

12.8% (n=80)

17.6% (n=5092; r=1)

Fibronectin type III (IPR003961)

9.63% (n=60)

2.9% (n=842; r=5)

Ankyrin repeat (IPR002110)

5.3% (n=33)

0.9% (n=278; r=14)

Nebulin 35 residue motif (IPR000900)

4.5% (n=28)

n.i.

  1. (n.i.= not indicated; n= number of occurrences; r= rank in the human proteome).