From: Kelch proteins: emerging roles in skeletal muscle development and diseases
Gene | Protein | Function | Expression |
---|---|---|---|
KLHL19 | KLHL19, KEAP1 | Oxidative stress and insulin signaling in muscle cells[32] | Ubiquitous[33] |
KLHL31 | KLHL31 | Skeletal muscle, heart (low levels in brain, kidney, and liver)[29] | |
KLHL39 | KLHL39, IVNS1ABP | Protection against drug-induced cardiomyopathy[35] | Ubiquitous[36] |
KLHL40 (KBTBD5) | KLHL40 | Skeletal muscle[14] | |
KLHL41 (KBTBD10 , KRP1) | KLHL41, Sarcosin | Skeletal muscle differentiation and myofibril assembly[22, 38, 39] | Skeletal muscle, lungs[22] |
MKLN1 | MKLN1, Muskelin | Muscle cell adhesion and extracellular communication[40] | |
KLHDC1 | KLHDC1 | Skeletal muscle[42] | |
KLHDC2 | KLHDC2 | Skeletal muscle[42] |