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Table 1 Kelch family proteins in skeletal muscle development

From: Kelch proteins: emerging roles in skeletal muscle development and diseases

Gene

Protein

Function

Expression

KLHL19

KLHL19, KEAP1

Oxidative stress and insulin signaling in muscle cells[32]

Ubiquitous[33]

KLHL31

KLHL31

Skeletal and cardiac muscle myogenesis[29, 34]

Skeletal muscle, heart (low levels in brain, kidney, and liver)[29]

KLHL39

KLHL39, IVNS1ABP

Protection against drug-induced cardiomyopathy[35]

Ubiquitous[36]

KLHL40 (KBTBD5)

KLHL40

Skeletal muscle differentiation[14, 37]

Skeletal muscle[14]

KLHL41 (KBTBD10 , KRP1)

KLHL41, Sarcosin

Skeletal muscle differentiation and myofibril assembly[22, 38, 39]

Skeletal muscle, lungs[22]

MKLN1

MKLN1, Muskelin

Muscle cell adhesion and extracellular communication[40]

Skeletal muscle, brain[40, 41]

KLHDC1

KLHDC1

Muscle cell migration and differentiation[42, 43]

Skeletal muscle[42]

KLHDC2

KLHDC2

Muscle cell migration and differentiation[42, 43]

Skeletal muscle[42]