Figure 2
From: Facioscapulohumeral dystrophy: the path to consensus on pathophysiology
Schematic of novel transcription start sites regulated by DUX4. Upper panel shows the standard transcriptional start site for HEY1 and its intron-exon structure in green. The lower panel shows the transcript induced by DUX4 that originates in a retrotransposon LTR (blue) and splices into novel exons (uncolored) and the annotated HEY1 exons (green) to produce a predicted protein similar to HEY1.