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Table 1 Cumulative muscle damage in exercised mdx mice treated or not with andrographolide

From: Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

  Necrosis Regeneration Cumulative damage
mdx + vehicle 7.63 ± 0.85 42.14 ± 4.03 49.77 ± 4.61
mdx + andrographolide 4.14 ± 0.51b 30.23 ± 2.86a 34.37 ± 2.97a
  1. Cumulative skeletal muscle damage in mdx mice consists of active myofiber necrosis plus the areas of subsequent regeneration (new myofibers). Values shown are average percentage (%) of whole cross-sectional area +/− SEM (values were analyzed by a t-test, n = 5, aP < 0.05) [38]. bP < 0.01.