Figure 8

sox6 mutant adults are small and have spinal deformities. (A) sox6 mutant fish are significantly smaller than siblings by 1 month. Student’s two-tailed, unpaired t-test P <0.05, error bars represent standard deviation, sibling n = 17, mutant n = 17, asterisk indicates significance. (B and C) By 80 dpf, there is clear curvature of the spine in all surviving homozygous sox6 mutant fish (C) as compared to siblings (B).