Muscle phenotypes in young and old
muscles. (A) Hematoxylin and eosin staining of cross sections of gastrocnemius muscle in young (6 weeks) and old (6 months) mdx and Galgt1
mdx animals. (B) Average percentage central nuclei in mdx and Galgt1
mdx gastrocnemius at 6 weeks and 6 months of age. (C) Average Mini-Feret myofiber diameters in mdx and Galgt1
mdx gastrocnemius muscle at 6 weeks and 6 months of age. (D) Average percentage of non-muscle area present in muscle sections in mdx and Galgt1
−/−mdx muscles at 6 weeks and 6 months of age. Errors in (B)–(D) are SEM from six muscles per condition with 1,600–3,200 total myofibers counted per condition. *P < 0.05, **P < 0.01, ***P < 0.001, NS not significant, Bar is 50 μm.