Figure 8
From: PGC-1α modulates denervation-induced mitophagy in skeletal muscle
Elevated PGC-1α results in greater basal and denervation-induced autophagy protein expression. (A-E) Blots and quantification of autophagic proteins in control (Con), denervated (Den) WT and PGC-1α Tg (Tg) animals. (A) Representative blots. Quantification of (B) LC3BI, (C) LC3BII, (D) Nix, and (E) p62. *P < 0.05 significant difference between Con and Den. †P < 0.05 significant effect of genotype. GAPDH was used as a loading control (n = 3 to 5 for all groups). AU, arbitrary units; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.