From: Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice
EDL (4 to 6 months) | Mitochondrial alterations (%) | Total % of altered mitochondria | |||
---|---|---|---|---|---|
 | Swollen mitochondria | Containing vacuole | Disruption of ext. membr./int. cristae | Containing myelin figures | |
WT | 1.45 | 0.80 | 0.24 | 0.16 | 2.65 ± 0.5 |
CASQ1-null | 6.22** | 5.66** | 1.96** | 1.23** | 15.08 ± 0.9** |