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Figure 6 | Skeletal Muscle

Figure 6

From: The effect of the muscle environment on the regenerative capacity of human skeletal muscle stem cells

Figure 6

CD133+ cells contribute to more satellite cells in cryodamaged Rag2-/γ chain-/C5- than in mdx nude muscle. (a-e) Representative images showing donor-derived satellite cells that express Pax7 (green, (b)) and human lamin A/C (red, (c)), located underneath the basal lamina (cyan, (d)) of the muscle fibres. Nuclei were counterstained with DAPI (blue, (a)). (e) The merged image of (a-d). Scale bar = 10 μm. (f) and (g): quantification of the percentage of donor derived satellite cells in cryodamaged (f) or irradiated+cryodamaged (Irra+Cryo, (g)) muscles of Rag2-/γ chain-/C5- and mdx nude mice. *P < 0.05. Rag, recombinase-activating gene.

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Skeletal Muscle

ISSN: 2044-5040

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