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Table 1 The transplantation efficiency of human muscle stem cells is affected by the type of injury

From: The effect of the muscle environment on the regenerative capacity of human skeletal muscle stem cells

Donor cells Donor contribution Injury model P value (one-way ANOVA)
Host mouse Number of donor nuclei or fibres (mean ± SEM ( n ))
Irradiation Cryodamage Irra+Cryo
Pericytes mdx nude Human lamin A/C+ nuclei 51.83 ± 20.01 (6) 84.17 ± 13.97 (6) 110.4 ± 56.64 (5) 0.465
S+L fibres 3.000 ± 1.506 (6) 27.83 ± 6.421 (6) 18.20 ± 7.933 (5) 0.0214*
CD133+ mdx nude Human lamin A/C+ nuclei 32.50 ± 16.66 (6) 248.0 ± 35.39 (6) 195.2 ± 48.64(5) 0.0012**
S+L fibres 14.50 ± 6.980 (6) 107.0 ± 14.14 (6) 113.8 ± 25.39 (5) 0.0008***
Pericytes Rag2-/γ chain-/C5- Human lamin A/C+ nuclei 79.55 ± 31.13(11) 270.9 ± 76.12 (8) 270.1 ± 69.51 (11) 0.0424*
S+L fibres 15.64 ± 6.33 (11) 132.6 ± 35.37 (8) 69.82 ± 21.01 (11) 0.0036**
CD133+ Rag2-/γ chain-/C5- Human lamin A/C+ nuclei 98.83 ± 44.22 (6) 623.2 ± 117.3 (6) 569.3 ± 104.8 (6) 0.0023**
S+L fibres 18.00 ± 6.583 (6) 191.3 ± 37.04 (6) 146.7 ± 18.38 (6) 0.0004***
  1. *P < 0.05;**P < 0.01; ***P < 0.001.
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