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Table 1 The transplantation efficiency of human muscle stem cells is affected by the type of injury

From: The effect of the muscle environment on the regenerative capacity of human skeletal muscle stem cells

Donor cells

Donor contribution

Injury model

P value (one-way ANOVA)

Host mouse

Number of donor nuclei or fibres (mean ± SEM ( n ))

Irradiation

Cryodamage

Irra+Cryo

Pericytes mdx nude

Human lamin A/C+ nuclei

51.83 ± 20.01 (6)

84.17 ± 13.97 (6)

110.4 ± 56.64 (5)

0.465

S+L fibres

3.000 ± 1.506 (6)

27.83 ± 6.421 (6)

18.20 ± 7.933 (5)

0.0214*

CD133+ mdx nude

Human lamin A/C+ nuclei

32.50 ± 16.66 (6)

248.0 ± 35.39 (6)

195.2 ± 48.64(5)

0.0012**

S+L fibres

14.50 ± 6.980 (6)

107.0 ± 14.14 (6)

113.8 ± 25.39 (5)

0.0008***

Pericytes Rag2-/γ chain-/C5-

Human lamin A/C+ nuclei

79.55 ± 31.13(11)

270.9 ± 76.12 (8)

270.1 ± 69.51 (11)

0.0424*

S+L fibres

15.64 ± 6.33 (11)

132.6 ± 35.37 (8)

69.82 ± 21.01 (11)

0.0036**

CD133+ Rag2-/γ chain-/C5-

Human lamin A/C+ nuclei

98.83 ± 44.22 (6)

623.2 ± 117.3 (6)

569.3 ± 104.8 (6)

0.0023**

S+L fibres

18.00 ± 6.583 (6)

191.3 ± 37.04 (6)

146.7 ± 18.38 (6)

0.0004***

  1. *P < 0.05;**P < 0.01; ***P < 0.001.