Table 3 Pax7+ myogenic cells in muscles of Rag2-/γ chain-/C5- and mdx nude mice that had been grafted with CD133+ cells
Injury models | Host mouse (mean ± SEM ( n )) | P value (Mann-Whitney test) | ||
|---|---|---|---|---|
Rag2-/g chain-/C5- | mdx nude | |||
Total Pax7+ cells | Cryodamage | 9.508 ± 1.933 (6) | 8.071 ± 1.205 (6) | 0.3095 |
Irra+Cryo | 3.320 ± 0.7494 (6) | 3.464 ± 0.7909 (6) | 0.9372 | |
Host Pax7+ cells | Cryodamage | 7.392 ± 1.381 (6) | 87.67 ± 13.10 (6) | 0.9372 |
Irra+Cryo | 0.7452 ± 0.217 (6) | 3.019 ± 0.738 (6) | 0.0411* | |
Donor Pax7+ cells | Cryodamage | 2.116 ± 0.7793 (6) | 0.5501 ± 0.3004 (6) | 0.0931 |
Irra+Cryo | 2.574 ± 0.8427 (6) | 0.4451 ± 0.2199 (6) | 0.0152* | |
Percentage of donor Pax7+ cells | Cryodamage | 20.67 ± 4.430 (6) | 5.868 ± 2.840 (6) | 0.026* |
Irra+Cryo | 67.98 ± 10.45 (6) | 11.46 ± 5.248 (6) | 0.0064** | |
Donor-derived satellite cells | Cryodamage | 1.400 ± 0.6211 (6) | 0.2220 ± 0.1234 (6) | 0.0303* |
Irra+Cryo | 0.7798 ± 0.2294 (6) | 0.1331 ± 0.0474 (6) | 0.0173* | |