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Table 1 Fiber-type specific gene expression changes in iMS- Bmal1 −/−

From: The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle

Gene symbol Fast or slow Gene description ΔExpression (Tam/Veh) Student’s t test
Atp2a1 Fast Calcium handling 0.99 ns
Atp2a2 Slow Calcium handling 1.06 ns
Calm3 Fast Calcium handling 0.84 ***
Casq1 Fast Calcium handling 1.00 ns
Casq2 Slow Calcium handling 2.89 ***
Itpr1 Fast Calcium handling 1.05 ns
Pvalb Fast Calcium handling 1.02 ns
Ankrd2 Slow Nuclear receptor 1.66 *
Csrp3 Slow Nuclear receptor 2.13 **
Fhl1 Slow Nuclear receptor 1.28 **
Nfatc2 Slow Nuclear receptor 0.88 ns
Pdlim1 Slow Nuclear receptor 1.51 ***
Ppara Slow Nuclear receptor 1.23 *
Ppargc1a Fast Nuclear receptor 0.83 *
Sos2 Fast Nuclear receptor 0.84 ***
  1. Average gene expression changes of calcium handling and nuclear receptor genes in iMS-Bmal1 −/−. ns, non-significant; *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.