Fig. 9
From: A differential response to newt regeneration extract by C2C12 and primary mammalian muscle cells
Treatment with newt extract induced fragmentation of primary myotubes. Primary myotubes did not re-enter the cell cycle but were induced to fragment following treatment with 0.3Â mg/ml of extract. a Visible changes to myotube morphology and structure were seen by treatment with extract. b Cell counts showed a significant drop in the number of myotubes and a significant increase in the number of myocytes following treatment with extract. This suggests that fragmentation is occurring