Fig. 1
From: Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment
Actomyosin ATPase and sarcoplasmic reticulum (SR) Ca2+-ATPase activities are decreased in AIA EDL muscles. Representative Coomassie brilliant blue staining of myofibrillar proteins (a), percentage distribution of myosin heavy chain (MyHC) and actin content in total myofibrillar proteins (b), and actomyosin ATPase activity (c). Electrophoretically separated MyHC isoforms (d) and percentage distribution of MyHC isoforms (e): I, slow isoform and IIa, IId/x, and IIb, fast isoforms. Representative Western blots of ryanodine receptor (RyR1), dihydropyridine receptor α2 subunit (DHPR), and SR Ca2+-ATPase (SERCA) 1 (f), the expression levels of these proteins normalized to actin content (g), and SERCA activity (h). Control (CNT), white bars; AIA, black bars. Data are presented as mean ± SEM for three to seven muscles in each group. *P < 0.05 versus CNT