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Fig. 1 | Skeletal Muscle

Fig. 1

From: Upregulated IL-1β in dysferlin-deficient muscle attenuates regeneration by blunting the response to pro-inflammatory macrophages

Fig. 1

Characterization of M1 and M2 macrophages in response to differential stimuli. Bone marrow-derived macrophages were either unstimulated (Mϕ), stimulated with LPS, to induce M1, or IL-4 to induce the M2a phenotypes, respectively. a M1 phenotype validation using qRT-PCR for IL-12, b TNFα, and c iNOS. d ELISA analysis for IL-12/23p40 in M1, M2a, or control (Mϕ) macrophages. e Gene expression of Fizz-1 by qRT-PCR in M1, M2a, or control (Mϕ) macrophages. f Gene expression of IL-4 by qRT-PCR in M1, M2a, or control (Mϕ) macrophages

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