Fig. 2

Genomic structure of the targeted dysferlin locus in the Dysf ^tm1Kcam mice. a Schematic drawing of the locus analyzed by PCR and sequencing. b Schematic drawing of the sequenced region, with the four PCR products generated (covering overlapping genomic regions of the targeted dysferlin locus) shown on gel and schematically. Indicated in the drawing are the neo cassette, the inverted short arm harboring exon 55, and part of the TK cassette.