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Table 2 Top 50 genes significantly associated with age across 361 samples

From: A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging

Gene Min (p) Max |β|
H3F3B 3.39E-13 0.0098
AHNAK 6.87E-12 0.0086
HOXB2 1.01E-11 −0.0184
CRIM1 5.34E-11 0.0124
NAP1L1P3 9.74E-11 0.0154
ARFGAP2 3.56E-10 0.0069
WDR6 4.47E-10 0.0069
DLEU1 8.61E-10 −0.0117
USP6 1.43E-09 0.0133
TCF25 2.70E-09 0.0064
SCN4B 3.13E-09 −0.0289
ZNF274 3.87E-09 0.0129
HDAC4 4.04E-09 0.0155
SH3BP5 5.04E-09 0.0114
SART3 5.32E-09 0.0050
CASC3 9.73E-09 0.0061
CIRBP 1.14E-08 0.0091
HIST1H2BN 1.49E-08 −0.0065
FUBP1 1.74E-08 0.0058
FAM171A1 1.94E-08 −0.0113
NPPA 1.97E-08 −0.0048
TMEM59L 2.39E-08 −0.0080
UBE2O 2.79E-08 −0.0060
FEZ2 2.83E-08 0.0126
ALS2CL 3.15E-08 −0.0063
C1S 3.22E-08 0.0137
RXRG 3.23E-08 −0.0095
NT5C2 3.64E-08 0.0115
TRMT112 4.42E-08 0.0116
PRNP 4.68E-08 0.0094
NOL9 6.31E-08 0.0049
RBM10 6.66E-08 0.0056
ANP32B 6.71E-08 0.0092
TOMM40L 6.74E-08 −0.0144
HTR5A 7.21E-08 −0.0051
SEC24C 7.78E-08 0.0060
BUB3 7.98E-08 0.0036
DAAM2 8.92E-08 −0.0091
HSPA1A 8.93E-08 0.0091
SEZ6L2 9.12E-08 −0.0046
MRPL4 9.38E-08 −0.0080
CMC2 1.04E-07 −0.0091
NR1D1 1.04E-07 −0.0054
ENDOG 1.11E-07 −0.0126
MRPL48 1.25E-07 −0.0066
FRAT2 1.31E-07 −0.0064
SYNRG 1.31E-07 0.0040
PPIC 1.38E-07 −0.0076
POMT1 1.47E-07 0.0061
DECR2 1.65E-07 0.0043
  1. The minimum p and maximum β values were calculated for genes present in both array datasets, adjusted for sex and study effect. A positive β value implicates increasing gene expression with age. For the full list of 957 genes, see Table S2 in Additional file 2