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Table 5 Of the 957 aging genes, 21 were significantly associated with physical capacity across 116 samples

From: A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging

Gene

p (age)

p (PC)

β (age)

β (PC)

SOCS2

5.51E-07

6.28E-08

−0.0034

0.0143

SLC16A10

0.000785

8.53E-07

0.00354

−0.02369

METTL7A

0.001265

1.22E-05

0.011168

−0.02183

CALU

0.00086

1.89E-05

−0.00311

0.009051

FEZ2

2.83E-08

3.46E-05

0.012589

−0.01958

DMRT2

0.000223

4.37E-05

−0.01035

0.018518

ITGA6

0.000564

6.32E-05

−0.00607

0.017743

MESP1

0.000246

8.97E-05

−0.00638

−0.00767

IP6K2

2.32E-06

0.000112

0.005743

−0.00807

ANKRD27

0.000118

0.000121

0.006005

−0.02111

MPC1

0.000705

0.000148

−0.00478

0.010666

PAF1

1.07E-06

0.000258

0.006852

−0.01292

SLIT2

0.000698

0.000297

0.009127

−0.01342

DDX24

2.01E-05

0.000318

0.004313

−0.00869

FAM53C

0.001351

0.000342

0.003416

−0.00845

CPSF7

0.000491

0.000405

0.003669

−0.00789

DGKD

0.000456

0.000838

0.00429

−0.01153

PHF20

0.001338

0.000871

0.00284

−0.00665

ABRA

0.001011

0.000952

0.014313

−0.01971

NT5C2

3.64E-08

0.000954

0.011521

−0.01262

DNAJB2

9.22E-07

0.000956

0.007196

−0.01217

  1. A positive β value implicates increasing gene expression with increased physical capacity, adjusted for study effect