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Fig. 2 | Skeletal Muscle

Fig. 2

From: CD49d is a disease progression biomarker and a potential target for immunotherapy in Duchenne muscular dystrophy

Fig. 2

Higher numbers of activated CD8+CD49d+ T cells in muscle of DMD patients with rapid progression. a Number of CD4+ and CD8+ T lymphocytes per inflammatory infiltrate. b Relative number of T cells simultaneously expressing CD49d and the T cell activation marker HLA-DR. The biopsies were performed at the beginning of the disease, and patients were divided into two groups according to the age when they became wheelchair bound. The number of DMD patients analyzed in each group appears in parentheses

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