Skip to main content
Fig. 2 | Skeletal Muscle

Fig. 2

From: Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation

Fig. 2

Validation of the p38α-dependent genes from expression arrays. a p38α-regulated genes were validated by qPCR in satellite cells derived from WT and p38α-deficient mouse muscles after 24 h in DM. b Genes regulated by chemical inhibition of p38α were validated by qPCR in differentiating C2C12 myoblasts (24 h DM) treated or not with SB. Different gene networks are regulated by p38α: muscle-specific and cell-cycle regulator genes, transcription factors, and genes encoding signaling proteins. Values are mean ± SEM of three independent experiments. Non-parametric Mann–Whitney U test was used for comparisons (P values <0.05)

Back to article page