TY - JOUR AU - Safdar, Adeel AU - Khrapko, Konstantin AU - Flynn, James M. AU - Saleem, Ayesha AU - De Lisio, Michael AU - Johnston, Adam P. W. AU - Kratysberg, Yevgenya AU - Samjoo, Imtiaz A. AU - Kitaoka, Yu AU - Ogborn, Daniel I. AU - Little, Jonathan P. AU - Raha, Sandeep AU - Parise, Gianni AU - Akhtar, Mahmood AU - Hettinga, Bart P. AU - Rowe, Glenn C. AU - Arany, Zoltan AU - Prolla, Tomas A. AU - Tarnopolsky, Mark A. PY - 2016 DA - 2016/01/31 TI - RETRACTED ARTICLE:Exercise-induced mitochondrial p53repairs mtDNA mutations in mutator mice JO - Skeletal Muscle SP - 7 VL - 6 IS - 1 AB - Human genetic disorders and transgenic mouse models have shown thatmitochondrial DNA (mtDNA) mutations and telomere dysfunction instigate the agingprocess. Epidemiologically, exercise is associated with greater life expectancyand reduced risk of chronic diseases. While the beneficial effects of exercise arewell established, the molecular mechanisms instigating these observations remainunclear. SN - 2044-5040 UR - https://doi.org/10.1186/s13395-016-0075-9 DO - 10.1186/s13395-016-0075-9 ID - Safdar2016 ER -