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Fig. 3 | Skeletal Muscle

Fig. 3

From: Decrease of myofiber branching via muscle-specific expression of the olfactory receptor mOR23 in dystrophic muscle leads to protection against mechanical stress

Fig. 3

mOR23 over-expression decreases myofiber branching after muscle regeneration. a Myofiber cross-sectional areas (CSA) of WT and TG1 gastrocnemius muscles were comparable before injury and after 2 weeks of regeneration. b Representative images of injured WT and TG1 muscles after 2 weeks of regeneration. Bar = 100 μm. c The percentage of regenerated myofibers was not significantly different in WT and TG1 muscles 3 weeks after muscle injury but TG1 muscles contained significantly less branched regenerated myofibers than WT muscles (d). e The number of branches per branched myofiber was also significantly decreased in injured TG1 muscles compared to WT (chi-square = 21.6, df = 3). n = 94–196 myofibers isolated per genotype and mouse. Data are mean ± SEM and n = 4–6 mice for each genotype with *p < 0.05

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