Fig. 1
Monitoring of hMPCs after transplantation. a Representative bioluminescence images of mice on days 0, 7, 28, and 49 post-transplantation with 2 × 106 hMPCs and a 4–5-week period of iNMES training (n = 4). Signal activity was detected in the regions of interest (ROI), encompassing the TA where the cells were originally injected, and quantified as photons/s. b Quantitative analysis of bioluminescence as a function of time following transplantation. Within the first week post-transplantation, <10 % of the original signal was detected in each of the three groups analyzed (group 1, N = 3; group 2, N = 7; group 3, N = 6). Less than 5 % of the transplanted hMPCs were retained at the end of the 7-week period following transplantation