Fig. 4

Size distribution of human muscle fibers cells in the xenografts. Minimum Feret’s diameters of the human muscle fibers were measured. Values were binned (1–9, 10–19, and ≥20 μm), and each bin was expressed as percent of the total. Significantly more (21 %) human muscle fiber in the mice of group 3 reached larger sizes (>20 μm) compared with those detected in mice from groups 1 and 2 (0 and 15 %, respectively) (chi-square test, p < 0.00001)