Fig. 1

DUX4-dependent luciferase activity of the four flavors of the DUX4 ChIP-seq motif. a DUX4 dose dependence of the four flavors of the DUX4 ChIP-seq consensus (left) and “half-sites” in one or two copies (right). RLU, relative luciferase units (normalized to Renilla luciferase). b DUX4-induced expression of luciferase reporters bearing various previously described DUX4 recognition motifs and mutations. Fold change is shown above each pair of assays. Note the log scale