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Table 1 CLAMS analysis of 10-week-old TSCmKO and RAmKO mice

From: Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

  Ctrl TSCmKO P Ctrl RAmKO P
Drink (ml/g/day) 0.31 ± 0.04 0.34 ± 0.06 NS 0.28 ± 0.04 0.30 ± 0.10 NS
Feed (g/g/day) 0.58 ± 0.17 0.58 ± 0.05 NS 0.42 ± 0.06 0.60 ± 0.14 *
CO2 (l/g/day) 0.37 ± 0.02 0.36 ± 0.03 NS 0.34 ± 0.04 0.41 ± 0.03 *
O2 (l/g/day) 0.39 ± 0.02 0.38 ± 0.02 NS 0.37 ± 0.05 0.44 ± 0.04 *
RER 0.94 ± 0.01 0.93 ± 0.03 NS 0.90 ± 0.01 0.91 ± 0.01 NS
Heat (kcal/h/g) 0.020 ± 0.00 0.019 ± 0.00 NS 0.026 ± 0.00 0.032 ± 0.00 *
X-amb (counts/h) 1078.9 ± 230.2 938.66 ± 314.8 NS 935.3 ± 357.3 938.7 ± 314.8 NS
Y-amb (counts/h) 187.9 ± 45.8 186.1 ± 51.6 NS 169.50 ± 93.17 140.19 ± 61.47 NS
  1. Student’s t test. Values represent mean ± SEM over a period of 3 days. Data presented are of male mice. X-amb and Y-amb refer to ambulatory movement measured by laser counts in X and Y coordinates
  2. NS not significant
  3. *p < 0.05 (n = 6)