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Table 2 CLAMS analysis of TSCmKO and RAmKO mice on a HFD

From: Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

  Ctrl TSCmKO P Ctrl RAmKO P
Drink (ml/g/day) 0.11 ± 0.04 0.16 ± 0.02 ** 0.15 ± 0.03 0.15 ± 0.06 NS
Feed (g/g/day) 0.21 ± 0.06 0.36 ± 0.12 * 0.27 ± 0.02 0.29 ± 0.13 NS
CO2 (l/g/day) 0.24 ± 0.03 0.32 ± 0.02 *** 0.29 ± 0.04 0.30 ± 0.04 NS
O2 (l/g/day) 0.31 ± 0.04 0.41 ± 0.02 ** 0.36 ± 0.04 0.40 ± 0.06 NS
RER 0.75 ± 0.01 0.77 ± 0.01 ** 0.79 ± 0.01 0.75 ± 0.01 **
Heat (kcal/h/g) 0.021 ± 0.00 0.028 ± 0.00 ** 0.019 ± 0.00 0.020 ± 0.00 NS
X-amb (counts/h) 557.5 ± 122.4 616.9 ± 80.6 NS 601.2 ± 103.8 294.7 ± 71.1 **
Y-amb (counts/h) 55.5 ± 7.8 79.1 ± 25.1 0.05 49.4 ± 10.5 42.3 ± 15.9 NS
  1. Student’s t test. Values represent mean ± SEM over a period of 4 days. Data presented are of male mice. X-amb and Y-amb refer to ambulatory movement measured by laser counts in X and Y coordinates
  2. NS not significant
  3. *p < 0.05
  4. **p < 0.01
  5. ***p < 0.001 (n = 6)