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Table 4 cobas analysis of 40-week-old TSCmKO and 20-week old RAmKO plasma

From: Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

Group ALTL (U/l) ASTL (U/l) Uric acid (μmol/l) Creatinine (μmol/l) LDH (mmol/l) TRIGL (mmol/l) HDL-Chol (mmol/l) LDL-Chol (mmol/l) Chol (mmol/l)
Ctrl 40.5 ± 4.3 65.7 ± 10.5 220.8 ± 54.0 10.7 ± 1.7 256.5 ± 76.1 1.1 ± 0.2 2.5 ± 0.5 0.3 ± 0.0 2.7 ± 0.6
TSCmKO 85.4 ± 13.6 308.9 ± 53.3 244.1 ± 60.6 16.6 ± 0.6 567.2 ± 74.2 1.1 ± 0.2 2.26 ± 0.3 0.4 ± 0.0 2.6 ± 0.3
P ** *** NS *** *** NS NS ** NS
Ctrl 31.5 ± 4.7 60.3 ± 14.3 115.3 ± 24.6 16.1 ± 1.7 278.0 ± 99.3 0.7 ± 0.5 2.0 ± 0.3 0.2 ± 0.0 2.3 ± 0.3
RAmKO 38.4 ± 8.7 95.2 ± 12.8 118.8 ± 28.5 15.5 ± 1.9 412.4 ± 58.7 0.5 ± 0.4 1.9 ± 0.2 0.2 ± 0.0 2.3 ± 0.3
P NS * NS NS NS NS NS NS NS
  1. Values represent mean ± SEM of male mice. Student’s t test
  2. NS not significant
  3. *p < 0.05
  4. **p < 0.01
  5. ***p < 0.001 (n = 5)