Skip to main content

Table 4 cobas analysis of 40-week-old TSCmKO and 20-week old RAmKO plasma

From: Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

Group

ALTL (U/l)

ASTL (U/l)

Uric acid (μmol/l)

Creatinine (μmol/l)

LDH (mmol/l)

TRIGL (mmol/l)

HDL-Chol (mmol/l)

LDL-Chol (mmol/l)

Chol (mmol/l)

Ctrl

40.5 ± 4.3

65.7 ± 10.5

220.8 ± 54.0

10.7 ± 1.7

256.5 ± 76.1

1.1 ± 0.2

2.5 ± 0.5

0.3 ± 0.0

2.7 ± 0.6

TSCmKO

85.4 ± 13.6

308.9 ± 53.3

244.1 ± 60.6

16.6 ± 0.6

567.2 ± 74.2

1.1 ± 0.2

2.26 ± 0.3

0.4 ± 0.0

2.6 ± 0.3

P

**

***

NS

***

***

NS

NS

**

NS

Ctrl

31.5 ± 4.7

60.3 ± 14.3

115.3 ± 24.6

16.1 ± 1.7

278.0 ± 99.3

0.7 ± 0.5

2.0 ± 0.3

0.2 ± 0.0

2.3 ± 0.3

RAmKO

38.4 ± 8.7

95.2 ± 12.8

118.8 ± 28.5

15.5 ± 1.9

412.4 ± 58.7

0.5 ± 0.4

1.9 ± 0.2

0.2 ± 0.0

2.3 ± 0.3

P

NS

*

NS

NS

NS

NS

NS

NS

NS

  1. Values represent mean ± SEM of male mice. Student’s t test
  2. NS not significant
  3. *p < 0.05
  4. **p < 0.01
  5. ***p < 0.001 (n = 5)