Fig. 6From: Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contracturesMyostatin mRNA levels in control, GRMD, and GRippet dogs. Values were significantly reduced in the CS of GRMD and GRippet dogs, compared to controls (p < 0.01 for both). A less pronounced reduction was seen in the VL of GRMD and GRippet dogs (p < 0.05 for both) versus controls. Values for the LDE and LHG did not differ among the three groups. No differences were seen between GRMD and GRippet dogs. All measurements are given in relation to HPRT values, which were normalized to 1Back to article page