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Table 4 Body-mass-corrected tetanic force (N/Kg) and ECD measurements in non-dystrophic control, GRMD (Mstn +/+), and GRippet (Mstn +/−) dogs

From: Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures

 

Flexion (mean ± SD)

Extension (mean ± SD)

ECD (10) (mean ± SD)

ECD (30) (mean ± SD)

Controls

1.54 ± 0.04a*,b*

3.16 ± 0.48b*

9.38 ± 6.18a*,b*

22.1 ± 11.6a*,b*

GRMD (Mstn+/+)

0.59 ± 0.32

1.93 ± 0.41

38.6 ± 14.8

64.2 ± 7.56

GRippet (Mstn+/−)

0.70 ± 0.41

1.92 ± 0.64

33.2 ± 2.77

61.7 ± 15.7

  1. ECD percent eccentric contraction decrement after 10 and 30 tetanic flexion contractions
  2. aSignificantly different (*p < 0.05) from GRMD dogs
  3. bSignificantly different (*p < 0.05) from GRippets