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Table 4 Body-mass-corrected tetanic force (N/Kg) and ECD measurements in non-dystrophic control, GRMD (Mstn +/+), and GRippet (Mstn +/−) dogs

From: Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures

  Flexion (mean ± SD) Extension (mean ± SD) ECD (10) (mean ± SD) ECD (30) (mean ± SD)
Controls 1.54 ± 0.04a*,b* 3.16 ± 0.48b* 9.38 ± 6.18a*,b* 22.1 ± 11.6a*,b*
GRMD (Mstn+/+) 0.59 ± 0.32 1.93 ± 0.41 38.6 ± 14.8 64.2 ± 7.56
GRippet (Mstn+/−) 0.70 ± 0.41 1.92 ± 0.64 33.2 ± 2.77 61.7 ± 15.7
  1. ECD percent eccentric contraction decrement after 10 and 30 tetanic flexion contractions
  2. aSignificantly different (*p < 0.05) from GRMD dogs
  3. bSignificantly different (*p < 0.05) from GRippets