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Fig. 7 | Skeletal Muscle

Fig. 7

From: Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy

Fig. 7

pS6 localizes to myofiber- and non-myofiber-specific niches in iliopsoas of Myf5/Fktn KO mice. a Images stained against phosphorylated S6 (S235/236) ribosomal protein (red) with basement membrane perlecan (green) and nuclear DAPI (blue) counterstains shown. Scale bar = 100 μm. b Plots comparing pS6-positive areas to percentages of regenerating fibers (eMHC, top) or to fibrotic areas (ColVI, bottom) in iliopsoas of VEH (left) and RAPA (right) KO mice. Pearson r value shown for all groups except RAPA KO eMHC (Spearman r shown, D’Agostino and Pearson omnibus normality test failed)

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