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Fig. 5 | Skeletal Muscle

Fig. 5

From: Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis

Fig. 5

EC coupling is not significantly impaired in early-symptomatic SOD1G93A FDB fibers. Representative Ca2+ transients elicited by 25 ms depolarizations from −80 to −60, −40, −20, 0, and 20 mV from fibers harvested from a wild-type mouse (a) and from an early-symptomatic SOD1G93A mouse (b). ΔF/F-V relationships are shown in (c)

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Skeletal Muscle

ISSN: 2044-5040

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