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Fig. 7 | Skeletal Muscle

Fig. 7

From: Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

Fig. 7

Partial restoration of dystrophin expression in the TA muscle from mdx mice injected with AAV1-U7ex23. a RT-PCR analysis of Dmd exon 23 skipping in mdx mice injected with AAV1-U7ex23. b Quantification of Dmd exon 23 skipping in mdx mice injected with AAV1-U7ex23, c Dystrophin total mRNA level in mdx mice injected with AAV1-U7ex23. d Western blot analysis of dystrophin protein expression in mdx mice injected with AAV1-U7ex23, e Quantification of dystrophin protein expression in mdx mice injected with AAV1 U7ex23. U7-ex23 AAV1-U7ex23, Mdx mdx muscle injected with saline, Mdx + U7ex23 mdx muscle injected with AAV1-U7ex23, c significant difference with non-injected muscle (p < 0.05). n = 6–10 per group

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Skeletal Muscle

ISSN: 2044-5040

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