Fig. 10

Effects of everolimus and CDD866 on phosphorylation of mTOR levels. Total mTOR (a) and phospho-mTOR (b). Animals received their last injection of CDD866 on day 13 and were euthanized on day 14. Values are expressed as means ± SEM (n = 5–10); ^** P < 0.01 versus non-tumor control; ⁺⁺ P < 0.01 versus non-tumor everolimus; ^xx P < 0.01 versus non-tumor CDD866; ^&& P < 0.01 versus CT-26 control; ^## P < 0.01 versus CT-26 everolimus; ^$$ P < 0.01 versus CT-26 CDD866