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Fig. 11 | Skeletal Muscle

Fig. 11

From: ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

Fig. 11

Effects of everolimus and CDD866 on inflammation and atrophy markers. IL-6 (a), MAFbx (b), and MuRF1 (c) levels. Animals received their last injection of CDD866 on day 13 and were euthanized on day 14. Values are expressed as means ± SEM; * P < 0.05, ** P < 0.01 versus non-tumor control; & P < 0.05, && P < 0.01 versus CT-26 control; ## P < 0.01 versus CT-26 everolimus; $$ P < 0.01 versus CT-26 CDD866

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