Fig. 3
From: p38α MAPK disables KMT1A-mediated repression of myogenic differentiation program
MKK6EE-p38α activation can rescue KMT1A suppressed muscle differentiation. a Western blot analysis of cell extracts from vector control C2-Em and Flag-KMT1A overexpressing C2-KMT1A-F cells generated via lentiviral delivery and the same cells after MKK6EE expression by same delivery system grown in GM or DM with or without SB. Probed with antibodies for indicated proteins where β-actin served as loading control. b Same as a except for western blot analysis, cells were fixed and evaluated for morphology by phase contrast microscopy and immunostained with anti-MyHC antibody (MF20)